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Meal Replacement Shakes: Clinical Evidence for Weight Management

UNO Nutrition Team2 min read

Meal replacement shakes have strong clinical evidence supporting their effectiveness for weight loss and weight management.

Clinical Evidence

Multiple systematic reviews and meta-analyses demonstrate meal replacements produce:

  • 2.5-3kg greater weight loss vs conventional diets at 1 year
  • Better adherence than calorie counting
  • Improved metabolic markers (blood sugar, cholesterol)
  • Easier portion control and calorie management

Effective Meal Replacement Formula

Macronutrient Profile:

  • Protein: 20-30g (30-40% of calories) for satiety and muscle preservation
  • Carbohydrates: 25-40g (complex, low GI)
  • Fats: 5-10g (essential fatty acids)
  • Total Calories: 200-400 per serving

Micronutrients:

  • 25-30% of daily vitamin and mineral requirements
  • Fiber (5-10g) for digestive health and satiety
  • Probiotics for gut health (optional)

Usage Strategies

Aggressive Weight Loss:

  • Replace 2 meals daily (breakfast + lunch)
  • Healthy dinner (400-600 calories)
  • Total intake: 1,200-1,500 calories
  • Expected loss: 1-2 kg per week

Moderate Weight Loss:

  • Replace 1 meal daily
  • Healthy snacks and meals
  • Total intake: 1,500-1,800 calories
  • Expected loss: 0.5-1 kg per week

Weight Maintenance:

  • Replace 1 meal 3-4x per week
  • Maintains weight after loss phase

Meal Replacement Manufacturing

UNO Nutrition manufactures complete meal replacement formulations for:

  • Medical weight loss programs (clinics, hospitals)
  • Pharmacy weight management brands
  • Corporate wellness programs
  • Fitness center nutrition programs

We handle full formulation development, nutrition facts compliance, and taste optimization for maximum patient compliance.

Need Custom Formulations?

Our B2B manufacturing team can develop custom nutrition formulations tailored to your brand's needs.

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