Ingredients

Protein Digestibility and Absorption: A Technical Guide

UNO Nutrition Team2 min read

Not all protein is created equal. Digestibility and bioavailability significantly impact protein quality and effectiveness.

Protein Quality Metrics

PDCAAS (Protein Digestibility-Corrected Amino Acid Score) - Range: 0-1.0 (1.0 = perfect protein) - Measures: Amino acid profile + digestibility - Limitation: Maxes out at 1.0, doesn't differentiate between excellent proteins

PDCAAS Scores:

  • Whey Protein: 1.0
  • Casein: 1.0
  • Soy Protein Isolate: 1.0
  • Pea Protein: 0.89
  • Rice Protein: 0.47
  • Wheat Protein: 0.25

DIAAS (Digestible Indispensable Amino Acid Score) - Newer Standard: More accurate than PDCAAS - Range: Can exceed 1.0 (better differentiation) - Measures: Ileal digestibility of individual amino acids - WHO Recommendation: Replacing PDCAAS

DIAAS Scores:

  • Whey Protein: 1.09-1.18
  • Milk Protein: 1.14
  • Egg Protein: 1.13
  • Pea Protein: 0.82
  • Rice Protein: 0.59

Factors Affecting Protein Digestibility

Processing Methods:

  • Heat treatment (improves digestibility up to a point)
  • Hydrolysis (breaks proteins into smaller peptides)
  • Fermentation (pre-digests proteins)

Food Matrix:

  • Fiber content (slows digestion)
  • Fat content (delays gastric emptying)
  • Anti-nutritional factors (phytates, trypsin inhibitors)

Individual Factors:

  • Age (elderly have reduced gastric acid)
  • Health status (GI diseases affect absorption)
  • Gut microbiome composition

Optimizing Protein Formulations

For Maximum Absorption: - Use protein isolates (higher digestibility) - Consider hydrolyzed proteins for clinical applications - Minimize anti-nutritional factors - Optimize processing conditions

For Specific Applications:

Fast Absorption (Post-Workout):

  • Whey protein isolate (DIAAS 1.18)
  • Hydrolyzed whey (even faster)
  • Minimal added fiber or fat

Slow Release (Overnight):

  • Micellar casein (DIAAS 1.14)
  • Combined with healthy fats for slower digestion

Clinical/Elderly:

  • Partially hydrolyzed proteins
  • High DIAAS scores
  • Easy to digest formulations

Protein Quality Manufacturing

UNO Nutrition's formulation expertise includes:

  • Selecting optimal protein sources for application
  • Balancing PDCAAS/DIAAS scores with cost
  • Processing optimization for digestibility
  • Quality testing and verification

Our protein sourcing includes premium whey isolates, micellar casein, and plant-based proteins with verified quality metrics.

Need Custom Formulations?

Our B2B manufacturing team can develop custom nutrition formulations tailored to your brand's needs.

Request Quote